New crystalline form of omeprazole

Details New crystalline form of omeprazole New crystalline form of omeprazole

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2284470

The present invention relates to a novel crystalline form of 5-methoxy-2-[[(4- methoxy-3,5-dimethyl-2-pyridinyl)methyl] sulfinyl]-1H-benzimidazole, know under the generic name omeprazole. Further, the present invention also relates to the use of the novel crystalline form of 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2- pyridinyl)methyl]sulfinyl]-1H-benzimidazole for the treatment of gastrointestinal disorders, pharmaceutical compositions containing it as well as processes for the preparation of the novel crystalline form of 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H- benzimidazole.

L'invention concerne une nouvelle forme cristalline de 5-méthoxy-2-[ [(4-méthoxy-3,5-diméthyl- 2-pyridinyl)méthyl] sulfinyl]-1<u>H</u>- benzimidazole, connu sous le nom générique d'omeprazole. Elle concerne également l'utilisation de cette nouvelle forme cristalline de 5-méthoxy-2-[ [(4-méthoxy-3,5-diméthyl- 2-pyridinyl)méthyl] sulfinyl]-1<u>H</u>- benzimidazole afin de traiter des troubles gastro-intestinaux, des compositions pharmaceutiques la contenant, ainsi que des procédés servant à préparer cette nouvelle forme cristalline de 5-méthoxy-2-[ [(4-méthoxy-3,5-diméthyl- 2-pyridinyl)méthyl] sulfinyl]-1<u>H</u>- benzimidazole.

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