New derivative of kojic acid and its use as a depigmenting...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 417/12 (2006.01) A61K 8/49 (2006.01) A61K 31/425 (2006.01) A61Q 19/02 (2006.01)

Patent

CA 2210365

The invention concerns a new derivative of kojic acid, with formula (I), and its use in a composition for topical application as a depigmentation and/or whitening agent for human skin (see fig I). The invention further concerns a procedure for depigmenting and/or whitening human skin, by applying to the skin a composition containing, in a physiologically acceptable medium, 2-oxo-thiazolidine-4-carboxylate of 5-hydroxy-4-oxo-4H-pyran-2yl-methyl, of formula (I).

L'invention se rapporte à un nouveau dérivé de l'acide kojique de formule (I) et à son utilisation dans une composition à application topique comme agent dépigmentant et/ou blanchissant de la peau humaine: (voir fig. I) Elle se rapporte également à un procédé de dépigmentation et/ou de blanchiment de la peau humaine, consistant à appliquer sur la peau une composition contenant, dans un milieu physiologiquement acceptable, le 2-oxo-thiazolidine-4- carboxylate de 5-hydroxy-4-oxo-4H-pyran-2-ylméthyle de formule (I).

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