New derivatives of 2-(1h)-quinoline, their preparation and...

C - Chemistry – Metallurgy – 07 – D

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C07D 215/36 (2006.01) A61K 31/47 (2006.01) C07D 221/06 (2006.01) C07D 401/04 (2006.01) C07D 471/04 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2209776

Compounds of formula (I): Image (I) where: R1, R2, R3, identical or different, represent one atom of hydrogen, of a halogen, an alkyl group, a nitro, cyano, aminosulfonyl, imidazolyl or pyrrolyl group, or, when two of these are situated on adjacent carbons, they form with the carbon atoms to which they are attached a benzene ring; R4 represents a hydroxy, alkoxy, phenoxy or amino group; their isomers and their addition salts with a pharmaceutically acceptable base. Medications.

Composés de formule (I): Image (I) dans laquelle: R1, R2, R3, identiques ou différents, représentent un atome d'hydrogène, d'halogène, un groupement alkyle, un groupement nitro, cyano, aminosulfonyl, imidazolyl ou pyrrolyl, ou bien, lorsque deux d'entre eux sont situés sur des carbones adjacents, forment avec les atomes de carbone auxquels ils sont attachés, un cycle benzénique, R4 représente un groupement hydroxy, alkoxy, phénoxy ou amino, leurs isomères ainsi que leurs sels d'addition à une base pharmaceutiquement acceptable. Médicaments.

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