New dipeptidyl peptidase iv effectors

Details New dipeptidyl peptidase iv effectors New dipeptidyl peptidase iv effectors

C - Chemistry, Metallurgy

07

D

C07D 277/04 (2006.01) A61K 31/40 (2006.01) A61K 31/425 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 45/06 (2006.01) C07D 295/18 (2006.01) C07D 295/185 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2333603

The present invention relates to dipeptide compounds and compounds analogous to dipeptide compounds that are formed from an amino acid and a thiazolidine or pyrrol-idine group, and salts thereof, and to the use of the compounds in the treatment of impaired glucose tolerance, glycosuria, hyperlipidaemia, metabolic acidoses, diabetes mellitus, diabetic neuropathy and nephropathy and also of sequelae of diabetes mellitus in mammals.

L'invention concerne des composés dipeptidiques ou des composés analogues à ces derniers, qui sont formés à partir d'un acide aminé et d'un groupe thiazolidine ou pyrrolidine, et leur sels. L'invention concerne également l'utilisation desdits composés pour le traitement de troubles de la tolérance glucidique, de la glucosurie, de l'hyperlipidémie, des acidoses métaboliques, du diabète sucré, de la neuropathie et de la néphropathie diabétiques, ainsi que des séquelles provoquées par le diabète sucré, chez les mammifères.

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