New disubstituted phenylpyrrolidines as modulators of...

C - Chemistry – Metallurgy – 07 – D

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C07D 207/12 (2006.01) A61K 31/40 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2690091

The present invention relates to the use of compounds which increase extracellular levels of catecholamines, dopamine and norepinephrine, in cerebral cortical areas of the mammalian brain, and more specifically to the use of 3-disubstituted phenyl-1 - pyrrolidinols for the treatment of central nervous system disorders.

La présente invention porte sur l'utilisation de composés qui augmentent les taux extracellulaires de catécholamines, de dopamine et de norépinéphrine, dans des zones corticales cérébrales du cerveau mammifère, et plus spécifiquement sur l'utilisation de 3-phényl disubstitué -1 - pyrrolidinols pour le traitement de troubles du système nerveux central.

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