New ds dna binding fluorescent dyes

C - Chemistry – Metallurgy – 09 – B

Patent

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Details

C09B 23/04 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2664434

The present invention is directed to a fluorescent dye comprising a benzothiazolium moiety and a pyrimidinium moiety connected by a mono-methine bridge, characterized in that (i) the 2-position of the pyrimidine carries a substituent which starts with a C-atom and (ii) the 5- and 6-positions of the pyrimidine ring are an integral part of a further aromatic ring structure.

La présente invention porte sur un colorant fluorescent comprenant une fraction benzothiazolium et une fraction pyrimidinium reliées par un pont mono-méthine, caractérisé par le fait que (i) la position 2 de la pyrimidine porte un substituant qui commence avec un atome de C et (ii) les positions 5 et 6 du noyau pyrimidine font partie intégrante d'une autre structure du noyau aromatique.

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