New ellipticine derivatives, their preparation process and...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/47 (2006.01) A61K 31/475 (2006.01) A61K 31/495 (2006.01) A61K 31/496 (2006.01) A61K 31/535 (2006.01) A61K 31/5377 (2006.01) A61K 31/54 (2006.01) A61K 31/541 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2227506

Compounds with the formula : Image in which R1, R2, R3, R4, R5, R6, R7, R8 and A are as defined in the description, their optical isomers, N-oxides and salts by addition, to a pharmaceutically accceptable acid or base, and their use as anti-tumour agents.

Les composés de formule: Image dans laquelle R1, R2, R3, R4, R5, R6, R7, R8 et A sont tels que définis dans la description, leurs isomères optiques, N-oxydes et sels d'addition, à un acide ou une base, pharmaceutiquement acceptables, et leur utilisation comme agents antitumoraux.

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