New esters derived from substituted phenyl-cyclohexyl compounds

Details New esters derived from substituted phenyl-cyclohexyl compounds New esters derived from substituted phenyl-cyclohexyl compounds

C - Chemistry, Metallurgy

07

C

C07C 219/26 (2006.01) A61K 31/24 (2006.01) C07C 219/28 (2006.01) C07C 219/30 (2006.01) C07D 207/337 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2349245

New esters derived from substituted phenyl-cyclohexyl compounds, derived from tramadol, process for obtaining such esters and use of said compounds for the fabrication of a medicament having analgesic properties. These new products having the general formula (I) have an analgesic activity which is higher than that of tramadol, a lesser toxicity and longer duration of activity.

L'invention concerne de nouveaux esters dérivés de composés phényl-cyclohexyle substitués provenant du tramadol, ainsi que les procédés de préparation et d'utilisation desdits composés en vue de la fabrication d'un médicament aux propriétés analgésiques. Ces nouveaux produits, de formule générale (I), présentent un pouvoir analgésique supérieur à celui du tramadol, une toxicité réduite et une durée d'action prolongée.

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