C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 498/18 (2006.01) C12P 17/18 (2006.01)
Patent
CA 2134844
This invention relates to a process of recovering a macrolide antibiotic, especially a tricyclic macrolide such as rapamycin from concentrates of fermentation broth extracts or mother liquors whereby acidic and/or basic components formed in the fermentation process are removed by utilizing aqueous base or acid extraction procedures from a water--immiscible solution of said concentrate and non-polar components are separated from the macrolide by selective solubility.
American Home Products Corporation
Torys Llp
Wyeth
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