New fatty acid derivatives

Details New fatty acid derivatives New fatty acid derivatives

C - Chemistry, Metallurgy

07

J

C07J 5/00 (2006.01) A01N 37/40 (2006.01) A01N 43/40 (2006.01) A01N 43/653 (2006.01) A01N 47/36 (2006.01) A01N 57/04 (2006.01) A61K 31/19 (2006.01) A61K 31/215 (2006.01) A61K 31/335 (2006.01) A61K 31/37 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/43 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/54 (2006.01) A61K 31/57 (2006.01) A61K 31/60 (2006.01) A61K 31/70 (2006.01) A61K 38/05 (2006.01) C07C 59/64 (2006.01) C07C 65/28 (2006.01) C07C 69/58 (2006.01) C07C 69/72 (2006.01) C07C

Patent

CA 2276694

The properties of biologically active compounds, for example drugs and agrochemicals, which contain in their molecular structure one or more functional groups selected from alcohol, ether, phenyl, amino, amido, thiol, carboxylic acid and carboxylic acid ester groups are modified by replacing one or more of these functional groups by a lipophilic group selected from those of the formula: RCOO-, RCONH-, RCOS-, RCH2O-, RCH2NH-, -COOCH2R, -CONHCH2R and -SCH2R, wherein R is a lipophilic moiety selected from cis-8-heptadecenyl, trans-8-heptadecenyl, cis-10-nonadecenyl and trans-10-nonadecenyl.

On modifie les propriétés de composés biologiquement actifs, par exemple des médicaments et des produits agrochimiques, qui contiennent dans leur structure moléculaire un ou plusieurs groupes fonctionnels choisis parmi des groupes acide carboxylique, ester d'acide carboxylique, alcool, éther, phényle, amino, amido et thiol, en remplaçant un ou plusieurs de ces groupes fonctionnels par un groupe lipophile choisi parmi les formules suivantes: RCOO-, RCONH-, RCOS-, RCH2O-, RCH2NH-, -COOCH2R, -CONHCH2R et -SCH2R, R étant un fragment lipophile choisi parmi cis-8-heptadécényle, trans-8-heptadécényle, cis-10-nonadécényle et trans-10-nonadécényle.

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