C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) C07K 14/31 (2006.01) C12N 1/21 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2294433
A new fibrinogen binding protein or polypeptide originating from coagulase negative staphylococci, biotechnological methods for producing said protein or polypeptide having fibrinogen binding activity and a recombinant DNA molecule coding for said protein (or fragments thereof), and micro-organisms (including viruses) containing this recombinant DNA molecule. The present invention further comprises the therapeutic and diagnostic use of said protein and/or DNA, e.g. a diagnostic kit for determining the presence and/or type of coagulase negative staphylococci and a vaccine composition, comprising said protein or DNA.
Nouvelle protéine ou nouveau polypeptide de fixation de fibrinogène tirant son origine des staphylocoques coagulase-négatifs, procédé bio-technologique de production de cette protéine ou de ce polypeptide ayant une activité de fixation du fibrinogène et une molécule d'ADN de recombinaison codant ladite protéine (ou des fragments de celle-ci), et micro-organismes (y compris des virus) contenant cette molécule d'ADN de recombinaison. La présente invention concerne également l'utilisation thérapeutique et diagnostique de ladite protéine et/ou l'ADN, par exemple un kit de diagnostic permettant de déterminer la présence et/ou le type de staphylocoques coagulase-négatifs et une composition de vaccin comprenant ladite protéine ou ADN.
Flock Jan-Ingmar
Frykberg Lars
Guss Bengt
Lindberg Martin
Nilsson Martin
Flock Jan-Ingmar
Frykberg Lars
Guss Bengt
Lindberg Martin
Nilsson Martin
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