C - Chemistry – Metallurgy – 08 – F
Patent
C - Chemistry, Metallurgy
08
F
C08F 220/12 (2006.01) A61K 9/58 (2006.01)
Patent
CA 2481139
The present invention provides a novel film coating dispersion obtainable by the polymerization of the following monomers in water: acrylic acid or an ester thereof in the range 40 to 80 % by weight; methacrylic acid or an ester thereof in the range 20 to 60 % by weight; and a polymerizable surfactant in the range 0.01 to 9 % by weight. The dispersion is suitable for coating pharmaceutical formulations to provide controlled release of the active ingredient.
La présente invention a trait à une nouvelle dispersion de pelliculage susceptible d'être obtenue par la polymérisation des monomères suivants dans l'eau : 40 à 80 % en poids d'acide acrylique ou d'un de ses esters ; 20 à 60 % en poids d'acide méthacrylique ou d'un de ses esters ; 0,01 à 9 % en poids d'un tensioactif polymérisable. La dispersion est apte au pelliculage de préparations pharmaceutiques pour conférer une libération contrôlée du principe actif.
Hjaertstam Lars Johan Pontus de Verdier
Karlsson Ola
Schantz Staffan
Astrazeneca Ab
Fetherstonhaugh & Co.
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