New formulation

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/4439 (2006.01) A61K 9/36 (2006.01) A61K 9/50 (2006.01) A61P 1/04 (2006.01)

Patent

CA 2376226

An oral dosage form comprising a core material coated with a semipermeable membrane wherein the core material comprises an active ingredient selected from the group of omeprazole, an alkaline salt thereof, S-omeprazole and an alkaline salt thereof, in admixture with one or more alkaline additives, one or more swelling agents, and optionally pharmaceutically acceptable excipients, and the dosage form is not enteric coated.

Cette invention concerne une forme de dosage oral qui comprend qui comprend un matériau central enrobé d'une membrane semi-perméable. Le matériau central comprend un principe actif choisi dans le groupe comprenant un oméprazole, un sel alcalin de celui-ci, un <i>S)</i>-oméprazole et un sel alcalin de celui-ci. Le principe actif est mélangé à un ou plusieurs additifs alcalins, à un ou plusieurs agents de gonflement et, éventuellement, à des excipients acceptables sur le plan pharmaceutique. Cette forme de dosage n'est pas entéro-soluble.

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