New glucocorticoids

Details New glucocorticoids New glucocorticoids

C - Chemistry, Metallurgy

07

K

C07K 5/10 (2006.01) A61K 31/56 (2006.01) A61K 38/07 (2006.01) C07J 41/00 (2006.01) C07J 43/00 (2006.01)

Patent

CA 2158643

Glucocorticoids have the general formula (I): R-Val-O- GC, in which O-GC stands for the rest of an anti-inflammatory 21-hydroxycorticoid, Val stands for a valine residue located at the 21st position of the corticoid and R stands for a hydrogen atom or for a hydrocarbon residue having up to 32 carbon atoms and if required substituted by hydroxy groups, amino groups, oxo groups and/or halogen atoms and/or interrupted by oxygen atoms, SO2 groups and/or NH groups. Also disclosed are the salts of said corticoids.

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