New heterocyclic carboxamides for use as thrombin inhibitors

Details New heterocyclic carboxamides for use as thrombin inhibitors New heterocyclic carboxamides for use as thrombin inhibitors

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/4155 (2006.01) A61K 31/422 (2006.01) A61P 7/02 (2006.01) C07D 405/14 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2727925

This invention relates to novel pharmaceutically useful compounds of formula (I), in particular compounds that are competitive inhibitors of trypsin-like serine proteases, especially thrombin, their use as medicaments, pharmaceutical compositions containing them and synthetic routes to their production.

Cette invention concerne de nouveaux composés pharmaceutiquement utiles de formule (I), en particulier des composés qui sont des inhibiteurs compétitifs des protéases à sérine ressemblant à la trypsine, en particulier la thrombine, leur utilisation comme médicaments, des compositions pharmaceutiques les contenant et les voies synthétiques de leur production. Formule (I)

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