New imidazoazole-alkenoic acid amide compounds

Details New imidazoazole-alkenoic acid amide compounds New imidazoazole-alkenoic acid amide compounds

C - Chemistry, Metallurgy

07

D

260/299, 260/389

C07D 487/04 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 1188690

ABSTRACT OF THE DISCLOSURE The invention relates to imidazoazolc-alkenoic acid amides of Formula (I) Image In one preferred compound X is N, Y is S, Rl is methyl, R2 is phenyl, R3 and R4 are both hydrogen and R5 is 2-ethylpipcridine. The alkenoic acid amides are useful as antihypertensive agents, diuretic agents and uricosuric agents. Also included in the invention are compositions containing said alkenoic acid amides and mcthods for the use of said alkenoic acid amides and the compositions containing them. In addition, the invention includes the intermediate carbonyl compounds of formula (II) and the intermediate alkenoic acids of Formula (V) as well as methods for their preparation.

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