C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/0784 (2010.01) A01N 1/02 (2006.01) A61K 39/00 (2006.01) C12N 1/04 (2006.01)
Patent
CA 2454734
The invention relates to dendritic cells irreversibly triggered to maturation, which are CD14 positive, which express MHC class I with a median fluorescence intensity less than about 1500 and CD86 with a median fluorescence intensity less than about 500, as determined by immunofluorescence staining and flow cytometry analysis.
L'invention concerne des cellules dendritiques déclenchées de façon irréversible à la maturation. Ces cellules sont CD14 positives et expriment MHC de classe I d'une intensité fluorescente médiane inférieure à environ 1500 et CD86 d'une intensité fluorescente médiane inférieure à environ 500, comme déterminé par coloration immunofluorescente et analyse de cytométrie de flux.
Abastado Jean-Pierre
Boccaccio Claire
Jacod Sylvie
Kaiser Andrew
Nardin Alessandra
Fetherstonhaugh & Co.
I.d.m. Immuno-Designed Molecules
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