New linker for bioactive agents

Details New linker for bioactive agents New linker for bioactive agents

A - Human Necessities

61

K

A61K 47/48 (2006.01) C07H 15/252 (2006.01) C07H 19/24 (2006.01)

Patent

CA 2067184

Conjugates of general formula (I): [A-O-W-Z]a-T wherein the moiety A-O- is the residue of drug of formula A-O-H in which -O-H is-a primary or secondary hydroxyl group; a is an integer of from 1 to 30; W is a group of general formula (2) wherein b is an integer of from 1 to 4, B represents a C1-C3 alkylene group and R1 and R2 each independently represent hy- drogen, halogen, alkyl, phenyl or substituted phenyl; Z is a spacer group and T is a carrier moiety.

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