New materials

Details New materials New materials

C - Chemistry, Metallurgy

08

L

C08L 101/02 (2006.01) A61L 27/26 (2006.01) A61L 33/06 (2006.01) C08L 23/06 (2006.01) C08L 23/12 (2006.01) C08L 23/34 (2006.01) C08L 75/04 (2006.01) C08L 81/06 (2006.01) C08L 101/00 (2006.01) C08L 33/06 (2006.01)

Patent

CA 2129905

The biocompatibility of various polymers are improved by blending with them a polymer including a zwitterionic groups. The zwitterionic group is usually an ammonium phosphate ester zwitterionic group and the polymer containing it may be produced by the free radical polymerisation of ethylenically unsaturated monomers including s monomer bearing the zwitterionic group. Blending of the two polymers may be achieved by dry blending particulate polymers m by mining the polymers in liquid dispersion or solution followed by removal of the liquid medium. The fibrinogen absorption and/or platelet activation of polymers may be reduced no a value of lean than 80 % or even less than 60 % of the base polymer by introducing amounts of mote than 10 % or more than 30 % of the zwitterionic group containing polymer. Preferred blends are of copolymers of 2- (methacryloyloxyethyl)-2'-(trimethylammonium)ethyl phosphate inner salt with higher alkyl (meth) acrylate, blended with olefin polymers and/or with rubber latices. The products may be used is medical devices in which they come into contact with bodily fluids, especially blood, plasma, serum and/or tear film.

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