New medical use of triazine derivatives

Details New medical use of triazine derivatives New medical use of triazine derivatives

A - Human Necessities

61

K

A61K 31/53 (2006.01) A61P 25/00 (2006.01) A61P 25/06 (2006.01) A61P 25/08 (2006.01) A61P 25/16 (2006.01) A61P 25/18 (2006.01) A61P 25/28 (2006.01) A61P 27/06 (2006.01) A61P 33/06 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2657577

Compounds of formula (I) especially where R1 is an optionally substituted alkyl, aralkyl or heterocyclyl-alkyl group, are shown to have activity as sodium channel blockers or as antifolates. Some novel compounds where R1 is an aralkyl or heterocyclyl-alkyl are disclosed.

L'invention concerne des composés de formule (I), formule selon laquelle en particulier R1 est un groupe alkyle, aralkyle ou hétérocyclyl-alkyle facultativement substitué, les composés ayant démontré qu'ils possèdent une activité d'agents de blocage des canaux sodiques ou une activité antifolate. Certains nouveaux composés dans lesquels R1 est un aralkyle ou un hétérocyclyl-alkyle sont divulgués.

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