New method for treatment of inflammatory diseases

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/395 (2006.01) A61P 19/02 (2006.01) C07K 16/40 (2006.01) C12N 9/20 (2006.01)

Patent

CA 2762187

The present invention provides methods and pharmaceutical compositions comprising antagonists to the protein Bile Salt-Stimulated Lipase (BSSL) for the prevention, prophylaxis and treatment of inflammatory diseases, such as rheumatoid arthritis. The invention further relates to pharmaceutical compositions comprising BSSL antagonists and their use in methods for the prevention, prophylaxis and treatment of inflammatory diseases, such as rheumatoid arthritis. Suitable BSSL antagonists to be used according to the invention are BSSL antibodies.

L'invention porte sur des méthodes et des préparations pharmaceutiques contenant des antagonistes de la protéine dite LSSB (Lipase stimulée par les sels biliaires) utilisables pour la prévention, la prophylaxie et le traitement de maladies inflammatoires telles que l'arthrite rhumatoïde. L'invention porte également sur des préparations pharmaceutiques contenant des antagonistes de la protéine dite LSSB (Lipase stimulée par les sels biliaires) utilisables pour la prévention, la prophylaxie et le traitement de maladies inflammatoires telles que l'arthrite rhumatoïde. Les antagonistes idoines de l'invention sont des anticorps de la LSSB.

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