New method of treatment

Details New method of treatment New method of treatment

A - Human Necessities

61

K

A61K 31/70 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2299320

The described invention relates to the treatment of hyperexcited sensory nervous function, e.g. neuropathic conditions in human subjects. The treatment is performed without inflicting painful side-effect to the patient, comprising intrathecal administration of the endogenous compound adenosine in a combination with a low dose of a local anaesthetic agent. It is demonstrated that the drug combination can intrathecally repeatedly be administered, providing inhibition of neuropathy without inducing side-effects from any of the two agents involved.

Cette invention concerne un procédé de traitement de la fonction nerveuse sensorielle hyper-excitée telle que des états névropathiques chez des sujets humains. Ce traitement se fait sans infliger d'effets secondaires douloureux au patient, et consiste à effectuer une administration intrathécale du composé endogène qu'est l'adénosine en combinaison avec une faible dose d'un anesthésique local. Il a été prouvé que cette combinaison médicamenteuse peut être administrée de manière répétée par voie intrathécale, ce qui permet d'inhiber la neuropathie sans qu'aucun des deux agents utilisés n'induisent d'effets secondaires.

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