New methods and kits for sequencing polypeptides

G - Physics – 01 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

G01N 33/68 (2006.01) G01N 33/483 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2414215

The present disclosure provides methods and kits which are useful for sequencing polypeptides. The methods involve derivatization of the N-terminus of the polypeptide or peptides thereof. The methods also involve derivatization of the epsilon amino group of the side-chain of the lysine containing polypeptide or peptides thereof. Mass spectral analysis of one or more of the resulting derivatized analytes provides spectra which are readily interpreted through the use of techniques well-known to the ordinarily skilled artisan. The present disclosure also describes kits which enhance convenient performance of the methods.

La présente invention concerne des procédés et des trousses destinés au séquençage de polypeptides. Les procédés de l'invention font appel à la dérivation de l'extrémité N-terminale du polypeptide ou des peptides de ce dernier, et également à la dérivation du groupe epsilon amino de la chaîne latérale de la lysine contenant le polypeptide ou les peptides de ce dernier. Une analyse par spectre de masse d'un ou plusieurs des analytes dérivés obtenus fournit des spectres que l'on peut facilement interpréter à l'aide de techniques connues de l'homme de l'art. L'invention se rapporte en outre à des trousses qui permettent de faciliter la mise en oeuvre des procédés précités.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

New methods and kits for sequencing polypeptides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with New methods and kits for sequencing polypeptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and New methods and kits for sequencing polypeptides will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-2023510

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.