C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/60 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) C07D 207/16 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 498/18 (2006.01)
Patent
CA 2197793
New compounds are disclosed for multi-merizing immunophilins and proteins containing immunophilin or immunophilin-related domains. The compounds are of the formula: M1-L-M2 where M1 and M2 are independently moieties of formula (II), in which R1, R2, n, X and Y are as defined.
On décrit de nouveaux composés pour multimériser des immunophilines ou des protéines contenant des immunophilines ou des domaines provenant d'immunophilines. Les composés ont la formule M<1>-L-M<2>, dans laquelle M<1> et M<2> sont des groupes indépendants ayant la formule (II), où R<1>, R<2>, n, X et Y sont définis dans la description.
Guo Tao
Holt Dennis A.
Keenan Terence
Laborde Edgardo
Schreiber Stuart
Ariad Gene Therapeutics Inc.
Ariad Pharmaceuticals Inc.
Gowling Lafleur Henderson Llp
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