New nimesulide salt cyclodextrine inclusion complexes

C - Chemistry – Metallurgy – 08 – B

Patent

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Details

C08B 37/16 (2006.01) A61K 31/63 (2006.01) A61K 47/40 (2006.01) A61K 47/48 (2006.01) C08B 37/00 (2006.01)

Patent

CA 2140887

Inclusion complexes of nimesulide alkali and alkaline earth metal salts of general formula (I) Image where A stands for an alkali and alkaline earth metal ion with cyclodextrins and cylcodextrin derivatives, compositions containing the same, processes for the preparation of the complexes by complexation of nimesulide salts and the compositions as well as methods to use the same as pharmaceuticals.

Complexes d'insertion de sels alcalins et alcalino-terreux de nimésulide, de formule générale (I) où A représente un ion alcalin ou un ion de métal alcalino-terreux, avec des cyclodextrines ou des dérivés de la cyclodextrine; compositions les contenant et procédés de préparation desdits complexes par complexification de sels de nimésulide, et préparation desdites compositions, ainsi que leur emploi en pharmacie.

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