C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/10 (2006.01) C07K 14/34 (2006.01) C12N 1/21 (2006.01) C12N 15/63 (2006.01) C12P 13/08 (2006.01)
Patent
CA 2315978
The invention relates to preferably recombinant DNA derived from Corynebacterium and replicable in coryneform microorganisms, which contains at least one nucleotide sequence that codes for the thrE gene, and a process for the production of L-threonine, which is characterised in that the following steps are carried out: a) Fermentation of microorganisms in which at least the thrE gene is amplified (overexpressed), optionally in combination with further genes, b) Enrichment of the L-threonine in the medium or in the cells of the microorganisms, and c) Isolation of the L-threonine.
Eggeling Lothar
Sahm Hermann
Thierbach Georg
Ziegler Petra
Degussa Ag
Degussa-Huls Aktiengesellschaft
Forschungszentrum Julich Gmbh
Marks & Clerk
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