New oligopeptides with affinity to opioid receptors

Details New oligopeptides with affinity to opioid receptors New oligopeptides with affinity to opioid receptors

C - Chemistry, Metallurgy

07

K

C07K 7/60 (2006.01) A61K 38/08 (2006.01) A61K 38/12 (2006.01) C07K 5/107 (2006.01) C07K 7/06 (2006.01) C07K 7/56 (2006.01) C07K 14/61 (2006.01) C07K 14/665 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2149899

2149899 9412532 PCTABS00032 Disclosed are novel oligopeptides with opioid receptor affinity which are straight or cyclic pentapeptides with the primary sequence backbone Tyr-X-Phe-Leu-Z, where X and Z denote amino acids or amino acid derivatives and/or analogues and where X and Z can be covalently coupled to provide a heterocyclic structure wherein Z is chosen among Cys, Glu, Gln or amino derivatives of Glu and Gln; X will be chosen among the amino acids or amino acid analogues Ser, Gly, Pro, AMCA, D-Ala, D- or L-ornithine, D- or L-2,4-diaminobutyric acid, D- or L-Lys and D- or L-Cys. Also disclosed are pharmaceutical preparations comprising said oligopeptides, which are potentially useful as analgesics for alleviating pain, for the treatment of depressions and for increasing the comfort of individuals suffering from extraordinary stress or shock.

Affiliated with

Also associated with

Rating

New oligopeptides with affinity to opioid receptors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with New oligopeptides with affinity to opioid receptors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and New oligopeptides with affinity to opioid receptors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1741708