New pharmaceutical compounds

Details New pharmaceutical compounds New pharmaceutical compounds

C - Chemistry, Metallurgy

07

D

C07D 307/82 (2006.01) A61K 31/343 (2006.01) A61K 31/381 (2006.01) A61K 31/428 (2006.01) A61P 25/16 (2006.01) C07D 277/02 (2006.01) C07D 333/62 (2006.01)

Patent

CA 2615466

Compounds of formula (I), wherein R1-R4, X, Y and Z are as defined in claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors.

Cette invention concerne des composés représentés par la formule (I), dans cette formule, R1-R4, X, Y et Z sont tels de définis dans les revendications. Les composés susmentionnés présentent une activité inhibitrices des enzymes COMT et ils sont utiles en tant qu'inhibiteurs de COMT.

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