New pharmaceutical formulation comprising cannabidiol and...

A - Human Necessities – 61 – K

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Details

A61K 31/05 (2006.01) A61K 31/352 (2006.01) A61K 36/185 (2006.01) A61P 3/04 (2006.01) A61P 19/08 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2692539

The present invention relates to a novel pharmaceutical formulation comprising a ratioed mix of: (i) one or more compounds that acts as an inverse agonist of the CB1 and/or CB2 receptor; and (ii) one or more compounds that acts as a neutral antagonist of the CB1 and/or CB2 receptor. Preferably both the inverse agonist of the CB1 and/or CB2 receptor and the neutral antagonist of the CB1 and/or CB2 receptor are cannabinoids. Preferably the cannabinoids are tetrahydrocannabidivarin (THCV) and cannabidiol (CBD).

La présente invention porte sur une nouvelle préparation pharmaceutique comprenant un mélange proportionné de : (i) un ou plusieurs composés qui agissent en tant qu'agoniste inverse du récepteur CB1 et/ou CB2; et (ii) un ou plusieurs composés qui agissent en tant qu'antagoniste neutre du récepteur CB1 et/ou CB2. De préférence, à la fois l'agoniste inverse du récepteur CB1 et/ou CB2 et l'antagoniste neutre du récepteur CB1 et/ou CB2 sont des cannabinoïdes. De préférence, les cannabinoïdes sont la tétrahydrocannabidivarine (THCV) et le cannabidiol (CBD).

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