New pharmacologically active catechol derivatives

Details New pharmacologically active catechol derivatives New pharmacologically active catechol derivatives

C - Chemistry, Metallurgy

07

D

C07D 277/36 (2006.01) A61K 31/41 (2006.01) A61K 31/515 (2006.01) C07D 233/96 (2006.01) C07D 239/40 (2006.01) C07D 239/54 (2006.01) C07D 239/60 (2006.01) C07D 239/62 (2006.01) C07D 263/46 (2006.01) C07D 277/20 (2006.01)

Patent

CA 2080917

Compounds of formula (I), wherein R1 is an electronegative substituent such as nitro, halogeno or cyano group and R2 is a group selected from (Ia) and (Ib), wherein R is hydrogen, or an alkyl, cycloalkyl, aralkyl or aryl group, wherein X1, X2, Y and Z are independently oxygen, sulfur of NR, wherein R may be as defined above and pharmaceutically acceptable esters and salts thereof are useful in the prevention or treatment of tissue damage induced by lipid peroxidation.

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