New phenylpiperazines

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 413/10 (2006.01) A61K 31/496 (2006.01) A61P 25/18 (2006.01) A61P 25/28 (2006.01) C07D 413/12 (2006.01) C07D 471/06 (2006.01)

Patent

CA 2411973

The invention relates to novel phenylpiperazine derivatives of the formulawherein:- R represents the group (a) or (b) as indicated in the description. These compounds are (partial) D2 receptor agonists and are usefull for treating CNS disorders, in particular Parkinson's disease.

La présente invention concerne de nouveaux dérivés de phénylpipérazine de formule (1) où :- R représente le groupe (a) ou (b) comme indiqué dans la description. Ces composés sont des agonistes du récepteur D¿2? (partiels) et sont utiles dans le traitement de troubles du système nerveux central (SNC), en particulier de la maladie de Parkinson.

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