New polymorphic form of 1- (4- { l- [ (e)...

Details New polymorphic form of 1- (4- { l- [ (e)... New polymorphic form of 1- (4- { l- [ (e)...

C - Chemistry, Metallurgy

07

D

C07D 205/04 (2006.01) A61K 31/397 (2006.01) A61P 21/00 (2006.01) A61P 29/00 (2006.01) A61P 31/06 (2006.01) A61P 31/08 (2006.01)

Patent

CA 2746764

This invention relates to a novel crystalline form (Form A) of 1-(4-{1-[(E)-4- cyclohexyl-3-trifluoromethyl-benzy- loxyimino]-ethyl}-2-ethyl-benzyl)-azetidine-3-carboxylic acid (Compound I), to pharmaceutical compositions comprising this crystalline form, to processes for forming it and to its use in medical treatment.

Cette invention concerne une nouvelle forme cristalline (Forme A) de l'acide 1-(4-{L-[(E)-4-cyclohexyl-3-trifluorométhyl-benzyloxyimino]-éthyl}-2-éthyl-benzyl)-azétidine-3-carboxylique (Composé I), des compositions pharmaceutiques comportant cette forme cristalline, des procédés de préparation de celle-ci et son utilisation dans un traitement médical.

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