New polymorphous form of doxazosine mesylate (form iii)

Details New polymorphous form of doxazosine mesylate (form iii) New polymorphous form of doxazosine mesylate (form iii)

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/505 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2225022

A new crystalline and anhydrous form of doxazosin mesylate of Formula I (see formula I) is described. The new form is crystalline and anhydrous and is characterised in its X-ray spectrum by the following reflex positions of high and medium intensity: 8.49° 21.03° 11.72° 22.87° 16.03° 25.02° 18.29° Owing to its crystalline properties, the new form of doxazosin mesylate according to the invention has surprising advantages both with regard to its synthesis and for pharmaceutical processing into solid dosage forms. A process for preparing the new form of doxazosin mesylate and medicaments containing the new form of doxazosin mesylate are also described.

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