New potically-active derivatives of (r) 5-pentylamino- 5-...

Details New potically-active derivatives of (r) 5-pentylamino- 5-... New potically-active derivatives of (r) 5-pentylamino- 5-...

C - Chemistry, Metallurgy

07

C

167/252, 260/508

C07C 237/22 (2006.01) A61K 31/195 (2006.01) C07C 233/12 (2006.01) C07C 237/00 (2006.01)

Patent

CA 1339917

There are described optically active derivatives of (R) 5-pentylamino-5-oxopentanoic acid and their pharmaceutically acceptable salts, having antagonistic activity towards cholecystokinin, and with the formula: (see fig. I) in which R1 is selected from the groups 2-naphthyl, 3,4-dichlorophenyl and 3,4-dimethylphenyl and R2 is a pentyl group or an alkoxyalkyl group with 4 carbon atoms, and in which the substituents on the central chiral group (marked with an asterisk in Formula (I)), have the R (rectus) configuration.

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