C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) C07B 57/00 (2006.01)
Patent
CA 2468688
The present invention relates to a process for the preparation of certain 2- pyridinyl)methyl]sulfinyl]-1H-benzimidazoles compounds. More specifically it relates to the preparation of an enantiomerically pure or optically enriched enantiomer of either omeprazole, pantoprazole, lansoprazole, or rabeprazole from a mixture containing the same using means for simulated moving bed chromatography.
La présente invention concerne un procédé destiné à la préparation de certains composés 2-pyridinyl)méthyl]sulfinyl]-1H-benzimidazoles. Plus spécifiquement, cette invention a trait à la préparation d'un énantiomère enrichi sur le plan optique ou pur sur le plan énantiomère d'oméprazole, de pantoprazole, de lansoprazole ou de rabéprazole à partir d'un mélange les contenant, à l'aide d'un dispositif de chromatographie à lit mobile simulé.
Andersson Shalini
Juza Markus
Astrazeneca Ab
Fetherstonhaugh & Co.
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