New process for preparing...

Details New process for preparing... New process for preparing...

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01)

Patent

CA 2217171

The process consists in reacting (-)-trans-N-(p-fluorophenyl)-3-[[3,4- (methylenedioxy)phenoxy]methyl]-piperidine acetate with 2-chloro- or 2-bromo- 4'-fluoroacetophenone, and the resulting compound can be isolated as a pharmaceutically acceptable addition salt by reaction with the corresponding acid.

L'invention concerne un procédé consistant à faire réagir l'acétate de (-)-trans-N-(p-fluorophényl)-3- 3,4-(méthylènedioxy)phénoxy méthyl pipéridine avec une 2-chloro- ou 2-bromo-4'-fluoroacétophénone et le composé résultant peut être isolé sous la forme d'un sel d'addition avec un acide acceptable sur le plan pharmaceutique.

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