New process for producing aminopiperazine derivatives

Details New process for producing aminopiperazine derivatives New process for producing aminopiperazine derivatives

C - Chemistry, Metallurgy

07

D

C07D 295/22 (2006.01) C07D 295/32 (2006.01)

Patent

CA 2304682

A new industrial process for producing compounds of general formula (I) and salts thereof, excellent in the yield and purity of the products, shortened in the process steps, and realized without the intervention of any nitroso compound. In said formula, R1 is lower alkyl, aryl, ar(lower)alkoxyl or heterocyclic group, each of which may be substituted with halogen; and R2 is cyclo(lower)alkyl, aryl or ar(lower)alkyl, each of which may be substituted with halogen.

Nouveau procédé industriel plus rapide et très rentable de production de composés de formule générale (I) d'excellente pureté et de sels de ceux-ci, sans qu'il soit nécessaire d'utiliser de composé nitroso. Dans ladite formule (I), R?1¿ représente un groupe hétérocyclique ou alkyle inférieur, aryle, ar-alcoxyle(inférieur), chacun pouvant être substitué par halogène; et R?2¿ représente cyclo-alkyle(inférieur), aryle ou ar-alkyle(inférieur), chacun pouvant être substitué par halogène.

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