New process for the preparation of a leukotriene antagonist

Details New process for the preparation of a leukotriene antagonist New process for the preparation of a leukotriene antagonist

C - Chemistry, Metallurgy

07

D

C07D 215/18 (2006.01)

Patent

CA 2589936

The present invention relates to a novel process for the preparation of montelukast sodium, a compound of Formula (1b)and precursors thereof. The invention further concerns the free acid of this compound in crystalline form, obtainable for the first time by the new process.

L'invention concerne un nouveau procédé permettant de préparer du sodium de montelukast, un composé de Formule (1b), et des précurseurs de ce dernier. L'invention concerne en outre l'acide libre de ce composé sous forme cristalline que l'on obtient pour la première fois par ce nouveau procédé.

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