New process for the preparation of azithromycin

Details New process for the preparation of azithromycin New process for the preparation of azithromycin

C - Chemistry, Metallurgy

07

H

C07H 17/00 (2006.01) C07H 17/08 (2006.01)

Patent

CA 2237747

The present invention describes a new process for the preparation of azithromycin from a suitable imino ether as precursor, characterised by the fact that the reduction and the reductive methylation of said imino ether are sequentially carried out with a noble metal catalyst and hydrogen in the presence of formaldehyde, or a source thereof, wherein both reactions can be conducted in the same reaction vessel.

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