New products of depolymerizing partially acetylated...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 9/24 (2006.01) A61K 8/73 (2006.01) A61K 47/36 (2006.01) A61L 15/28 (2006.01) A61L 17/10 (2006.01) A61Q 5/00 (2006.01) A61Q 11/00 (2006.01) C08B 37/08 (2006.01) C12N 1/20 (2006.01) C12N 9/42 (2006.01) C12P 19/26 (2006.01) C12Q 1/24 (2006.01) D21H 17/00 (2006.01) D21H 17/24 (2006.01) A61K 7/00 (1995.01)

Patent

CA 2143120

It has been found that various strains of the genus Thermoactinomyces produce substantial quantities of chitosanase when cultivated under appropriate conditions and that a new strain of Thermoactinomyces with the identification I-1052, Institut Pas- teur, Paris, is of special interest. A new thermostable enzyme has been isolated from the culture broth of this new strain. This new enzyme hydrolyzes chitosans with varying acetylation degrees. New depolymerized partially acetylated chitosan products are ob- tained by the use of these new enzymes and are characterized by their viscosity, molecular weight distribution and degree of acety- lation. Such new products can be used in pharmaceuticals and cosmetic compositions and as auxiliaries in paper making.

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