New protein conjugates and methods for their preparation

Details New protein conjugates and methods for their preparation New protein conjugates and methods for their preparation

A - Human Necessities

61

K

A61K 47/48 (2006.01) C07K 14/43 (2006.01)

Patent

CA 2655188

Reductive amination of peptide-derived aldehydes with anilines or heteroarylamines containing a property-modifying group provides new, hydrolytically stable protein conjugates, suitable for therapy.

Selon la présente invention, une amination réductive d'aldéhydes, dérivées de peptides pourvues d'anilines ou d'hétéroarylamines contenant un groupe modifiant les propriétés, permet d'obtenir de nouveaux conjugués de protéines hydrolytiquement stables et convenant aux thérapies.

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