C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/79 (2006.01) C07K 1/20 (2006.01)
Patent
CA 2608281
The invention relates to methods for purifying lactoferrin, stabilizing it in solution and improving its activity. In one embodiment of the present invention, it is provided methods for lactoferrin purification employing hydrophobic and/or hydrophilic adsorbent under specific conditions for maintaining or preserving lactoferrin protein stability. It is also provided a process to remove inhibitor of lactoferrin activity.
La présente invention concerne des méthodes de purification de la lactoferrine, sa stabilisation en solution et l'amélioration de son activité. Dans un mode d'application de la présente invention, sont décrites des méthodes de purification de la lactoferrine employant un adsorbant hydrophobe et/ou hydrophile dans des conditions spécifiques afin de maintenir ou de préserver la stabilité de la protéine de lactoferrine. Un procédé d'élimination de l'activité d'un inhibiteur de la lactoferrine est également décrit.
Aomari Hafida
Petitclerc Denis
Rowe Gerald
Crea Biopharma Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Sa Majeste La Reine Du Chef Du Canada Agriculture Et Agroaliment
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