A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/538 (2006.01) A61K 31/4747 (2006.01) C07D 231/14 (2006.01) C07D 401/04 (2006.01) C07D 403/06 (2006.01)
Patent
CA 2693187
The invention is concerned with novel pyrazol derivatives of formula (I), wherein formula (II), R1, R2, R3, R4, X and Y are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR-2 receptor and/or CCR-5 receptor and can be used as medicaments.
L'invention concerne de nouveaux dérivés pyrazolés de formule (I), dans laquelle R1, R2, R3, R4, X et Y sont tels que définis dans la description et dans les revendications, ainsi que des sels physiologiquement acceptables desdits dérivés. Ces composés sont des antagonistes du récepteur CCR-2 et/ou du récepteur CCR-5 et peuvent être utilisés comme médicaments.
Aebi Johannes
Binggeli Alfred
Green Luke
Hartmann Guido
Maerki Hans P.
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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