New pyrazole derivatives as angiotensin ii antagonist

Details New pyrazole derivatives as angiotensin ii antagonist New pyrazole derivatives as angiotensin ii antagonist

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/395 (2006.01) A61K 31/675 (2006.01) C07D 231/10 (2006.01) C07D 231/12 (2006.01) C07D 231/14 (2006.01) C07D 401/00 (2006.01) C07D 403/14 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01) C07F 5/02 (2006.01) C07F 7/22 (2006.01) C07F 9/6503 (2006.01)

Patent

CA 2173258

Compounds of general formula (I) and their salts and solvates are angiotensin II receptor antagonists and as such are useful in the treatment of hypertension, congestive heat failure and elevated intraocular pressure. Pharmaceutical compositions including these compounds and processes for their preparation are also provided.

Les composés de formule générale (I) (ainsi que leurs sels et solvates) sont des antagonistes du récepteur de l'angiotensine II et à ce titre sont utiles dans le traitement de l'hypertension, de l'insuffisance cardiaque congestive et de l'hypertension intra-oculaire. Des compositions pharmaceutiques renfermant ces composés et des procédés pour leur préparation sont également décrits.

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