New pyridazin-3(2h)-one derivatives

Details New pyridazin-3(2h)-one derivatives New pyridazin-3(2h)-one derivatives

C - Chemistry, Metallurgy

07

D

C07D 237/24 (2006.01) A61K 31/501 (2006.01) A61P 37/08 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 403/04 (2006.01) C07D 409/12 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2512099

Pyridazin-3(2H)-one derivatives of formula (I) are found to inhibit PDE-4:, wherein R1, R2 and R4 are organic radicals, R3 is a cyclic group, and R5 is an ester or an aryl or heteroaryl group.

L'invention concerne des dérivés de pyridazin-3(2H)one de formule (I) qui s'avèrent être des inhibiteurs de l'enzyme PDE-4. Dans ladite formule, R?1¿, R?2¿ et R?4¿ représentent des radicaux organiques, R?3¿ représente un groupe cyclique et R?5¿ représente un ester ou un groupe aryle ou hétéroaryle.

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