New pyridazine endothelin antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 403/04 (2006.01) A61K 31/506 (2006.01) A61P 9/08 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2357687

Compounds of formula (I) have affinity for endothelin receptors, are selective for ET A over ET B, and are potentially useful in the treatment of conditions mediated by endothelin.

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