New pyridine derivatives, processes for their preparation...

C - Chemistry – Metallurgy – 07 – D

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C07D 213/24 (2006.01) A61K 31/44 (2006.01) C07D 213/30 (2006.01) C07D 213/55 (2006.01) C07D 213/56 (2006.01) C07D 213/57 (2006.01) C07D 213/61 (2006.01) C07D 213/89 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2099603

2099603 9209598 PCTABS00013 The invention concerns compounds of formula (I), in which A is an alkylene rest with 1 to 3 carbon atoms or a -CH=CH- group; B is an oxygen atom or a valency bond; m is a whole number from 0 to 5; n is 0 or 1; X is a valency bond, an oxygen atom or a sulphur atom; Y is a valency bond or a phenylene rest optionally substituted by one or more C1-C6 alkyl, C1-C6 alkoxy, halogen, hydroxy or aminocarbonyl; Z is hydrogen, halogen, a C1-C6 alkyl or cyano; R is a CN, COOH, COO(C1-C6 alkyl), CONH-tetrazolyl, CON(OH)(C1-C6 alkyl) or 5-(1H)-tetrazolyl group and if Y is a phenylene rest, R may also be hydrogen; with the exception of the compound 4-[2-(4)-pyridinovinyl]-carboxymethoxybenzene. The invention also concerns physiologically tolerable salts of these compounds, methods of preparing them and drugs containing the compounds for the treatment of allergies.

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