New reagent for labelling nucleic acids

Details New reagent for labelling nucleic acids New reagent for labelling nucleic acids

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) C12Q 1/68 (2006.01) C40B 70/00 (2006.01) G01N 33/58 (2006.01) C07B 61/00 (2006.01)

Patent

CA 2356552

The present invention concerns a labelling reagent in which the label is bound via an amide bond and a linker to a residue of the molecule which is essentially characterized in that the N atom of the amide bond and the label are linked together directly by a covalent bond. In particular these are phosphoramidites or reactive supports suitable for nucleic acid synthesis. The invention also concerns processes for the production of such supports from suitable precursors.

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