New salt and polymorphs of a dpp-iv inhibitor

Details New salt and polymorphs of a dpp-iv inhibitor New salt and polymorphs of a dpp-iv inhibitor

C - Chemistry, Metallurgy

07

D

C07D 413/12 (2006.01) A61K 31/422 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2600203

The invention is concerned with (S)-l-{[2-(5-Methyl-2-phenyl-oxazol-4-yl)- ethylamino]-acetyl}-pyrrolidine-2-carbonitrile mesylate and crystalline polymorphs of this compound. This compound and its polymorphic forms exhibits superior properties compared to the previously known compounds and can be used as medicament for the treatment of disorders which are associated with DPP-IV.

L'invention concerne un (S)-l-{[2-(5-methyl-2-phenyl-oxazol-4-yl)- ethylamino]-acetyl}-pyrrolidine-2-carbonitrile mesylate et des polymorphes cristallins de ce composé. Ledit composé et ses formes polymorphes possèdent des propriétés supérieures à celles des composés antérieurs connus et peuvent être utilisés comme médicament pour traiter des troubles associés à DPP-IV.

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