New selective retinoid agonists

Details New selective retinoid agonists New selective retinoid agonists

C - Chemistry, Metallurgy

07

C

C07C 69/90 (2006.01) A61K 31/167 (2006.01) A61K 31/215 (2006.01) A61K 31/4418 (2006.01) A61P 11/00 (2006.01) A61P 17/00 (2006.01) C07C 57/26 (2006.01) C07C 61/29 (2006.01) C07C 63/64 (2006.01) C07C 63/66 (2006.01) C07C 69/86 (2006.01) C07C 233/63 (2006.01) C07D 213/80 (2006.01)

Patent

CA 2386793

This invention relates to new RAR selective retinoid agonists of formula (1) wherein the symbols are as defined in the specification to their pharmaceutically acceptable salts, individual isomers or to a racemic or non-racemic mixture; to pharmaceutical compositions containing them, and to methods for their use as therapeutic agents.

La présente invention concerne de nouveaux agonistes rétinoïdes sélectifs vis-à-vis des récepteurs de l'acide rétinoïque (RAR) correspondant à la formule (I) dans laquelle les symboles sont tels que définis dans la spécification de leurs sels, de leurs isomères acceptables sur le plan pharmaceutique ou d'un mélange racémique ou non racémique. L'invention concerne également des compositions pharmaceutiques les contenant, ainsi que des procédés d'utilisation de ceux-ci comme agents thérapeutiques.

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